Ontology highlight
ABSTRACT:
SUBMITTER: Crimmins MT
PROVIDER: S-EPMC2546575 | biostudies-literature | 2006 Apr
REPOSITORIES: biostudies-literature
Crimmins Michael T MT DeBaillie Amy C AC
Journal of the American Chemical Society 20060401 15
The enantioselective synthesis of bistramide A has been achieved with a longest linear sequence of 18 steps. The synthetic strategy involves the use of a distereoselective glycolate alkylation, an aldol addition of a chlorotitanium enolate of N-acylthiazolidinthione, and a Sharpless asymmetric epoxidation to synthesize the three key fragments. ...[more]