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Structure of flexible filamentous plant viruses.

ABSTRACT: Flexible filamentous viruses make up a large fraction of the known plant viruses, but in comparison with those of other viruses, very little is known about their structures. We have used fiber diffraction, cryo-electron microscopy, and scanning transmission electron microscopy to determine the symmetry of a potyvirus, soybean mosaic virus; to confirm the symmetry of a potexvirus, potato virus X; and to determine the low-resolution structures of both viruses. We conclude that these viruses and, by implication, most or all flexible filamentous plant viruses share a common coat protein fold and helical symmetry, with slightly less than 9 subunits per helical turn.

SUBMITTER: Kendall A

PROVIDER: S-EPMC2546986 | biostudies-literature | 2008 Oct

REPOSITORIES: biostudies-literature

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Structure of flexible filamentous plant viruses.

Kendall Amy A McDonald Michele M Bian Wen W Bowles Timothy T Baumgarten Sarah C SC Shi Jian J Stewart Phoebe L PL Bullitt Esther E Gore David D Irving Thomas C TC Havens Wendy M WM Ghabrial Said A SA Wall Joseph S JS Stubbs Gerald G

Journal of virology 20080730 19

Flexible filamentous viruses make up a large fraction of the known plant viruses, but in comparison with those of other viruses, very little is known about their structures. We have used fiber diffraction, cryo-electron microscopy, and scanning transmission electron microscopy to determine the symmetry of a potyvirus, soybean mosaic virus; to confirm the symmetry of a potexvirus, potato virus X; and to determine the low-resolution structures of both viruses. We conclude that these viruses and, b ...[more]

PMID: 18667514

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