The molecular basis for flexibility in the flexible filamentous plant viruses.
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ABSTRACT:
SUBMITTER: DiMaio F
PROVIDER: S-EPMC4527879 | biostudies-literature | 2015 Aug
REPOSITORIES: biostudies-literature
Publications
The molecular basis for flexibility in the flexible filamentous plant viruses.
DiMaio Frank F Chen Chun-Chieh CC Yu Xiong X Frenz Brandon B Hsu Yau-Heiu YH Lin Na-Sheng NS Egelman Edward H EH
Nature structural & molecular biology 20150713 8
Flexible filamentous plant viruses cause more than half the viral crop damage in the world but are also potentially useful for biotechnology. Structural studies began more than 75 years ago but have failed, owing to the virion's extreme flexibility. We have used cryo-EM to generate an atomic model for bamboo mosaic virus, which reveals flexible N- and C-terminal extensions that allow deformation while still maintaining structural integrity. ...[more]
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