Ontology highlight
ABSTRACT:
SUBMITTER: Bruce C
PROVIDER: S-EPMC2547851 | biostudies-literature | 2006 Jul
REPOSITORIES: biostudies-literature
Bruce Can C Shifman Mark A MA Miller Perry P Gulcicek Erol E EE
Analytical chemistry 20060701 13
The mass defect, that is, the difference between the nominal and actual monoisotopic masses, of a phosphorus in a phosphate group is greater than for most other atoms present in proteins. When the mass defects of tryptic peptides derived from the human proteome are plotted against their masses, phosphopeptides tend to fall off the regression line. By calculating the masses of all potential tryptic peptides from the human proteome, we show that regions of higher phosphorylation probability exist ...[more]