Unknown

Dataset Information

0

Practical synthesis of 7-prenylindole.


ABSTRACT: 7-Prenylindole is a useful building block for natural product and natural product analogue synthesis. While there have been several past syntheses of 7-prenylindole, none of them is very practical for its preparation on scale. Using an aza-Claisen rearrangement as the key step, 7-prenylindole has been prepared in four steps from indoline in 62% overall yield.

SUBMITTER: Xiong X 

PROVIDER: S-EPMC2556248 | biostudies-literature | 2007 Jul

REPOSITORIES: biostudies-literature

altmetric image

Publications

Practical synthesis of 7-prenylindole.

Xiong Xin X   Pirrung Michael C MC  

The Journal of organic chemistry 20070620 15


7-Prenylindole is a useful building block for natural product and natural product analogue synthesis. While there have been several past syntheses of 7-prenylindole, none of them is very practical for its preparation on scale. Using an aza-Claisen rearrangement as the key step, 7-prenylindole has been prepared in four steps from indoline in 62% overall yield. ...[more]

Similar Datasets

| S-EPMC4437221 | biostudies-literature
| S-EPMC7004131 | biostudies-literature
| S-EPMC7288699 | biostudies-literature
| S-EPMC6099835 | biostudies-other
| S-EPMC2897060 | biostudies-literature
| S-EPMC4685759 | biostudies-literature
| S-EPMC6142761 | biostudies-literature
| S-EPMC4144717 | biostudies-literature
| S-EPMC2755092 | biostudies-literature
| S-EPMC2764119 | biostudies-literature