Ontology highlight
ABSTRACT:
SUBMITTER: Brune V
PROVIDER: S-EPMC2556780 | biostudies-literature | 2008 Sep
REPOSITORIES: biostudies-literature
Brune Verena V Tiacci Enrico E Pfeil Ines I Döring Claudia C Eckerle Susan S van Noesel Carel J M CJ Klapper Wolfram W Falini Brunangelo B von Heydebreck Anja A Metzler Dirk D Bräuninger Andreas A Hansmann Martin-Leo ML Küppers Ralf R
The Journal of experimental medicine 20080915 10
The pathogenesis of nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL) and its relationship to other lymphomas are largely unknown. This is partly because of the technical challenge of analyzing its rare neoplastic lymphocytic and histiocytic (L&H) cells, which are dispersed in an abundant nonneoplastic cellular microenvironment. We performed a genome-wide expression study of microdissected L&H lymphoma cells in comparison to normal and other malignant B cells that indicated a relationship ...[more]