PhosphoScore: an open-source phosphorylation site assignment tool for MSn data.
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ABSTRACT:
SUBMITTER: Ruttenberg BE
PROVIDER: S-EPMC2562657 | biostudies-literature | 2008 Jul
REPOSITORIES: biostudies-literature
Publications
PhosphoScore: an open-source phosphorylation site assignment tool for MSn data.
Ruttenberg Brian E BE Pisitkun Trairak T Knepper Mark A MA Hoffert Jason D JD
Journal of proteome research 20080611 7
Correct phosphorylation site assignment is a critical aspect of phosphoproteomic analysis. Large-scale phosphopeptide data sets that are generated through liquid chromatography-coupled tandem mass spectrometry (LC-MS/MS) analysis often contain hundreds or thousands of phosphorylation sites that require validation. To this end, we have created PhosphoScore, an open-source assignment program that is compatible with phosphopeptide data from multiple MS levels (MS(n)). The algorithm takes into accou ...[more]
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