Ontology highlight
ABSTRACT:
SUBMITTER: Katoh A
PROVIDER: S-EPMC2572847 | biostudies-literature | 2008
REPOSITORIES: biostudies-literature
Katoh Akira A Chapman Peter J PJ Raymond Jennifer L JL
PloS one 20081104 11
To optimize motor performance, both the amplitude and temporal properties of movements should be modifiable by motor learning. Here we report that the modification of movement timing is highly dependent on signaling through P/Q-type voltage-dependent calcium channels. Two lines of mutant mice heterozygous for P/Q-type voltage-dependent calcium channels exhibited impaired plasticity of eye movement timing, but relatively intact plasticity of movement amplitude during motor learning in the vestibu ...[more]