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Dominance of blaCTX-M within an Australian extended-spectrum beta-lactamase gene pool.

ABSTRACT: bla(CTX-M) genes, particularly bla(CTX-M-15), are the dominant extended-spectrum beta-lactamase (ESBL) genes among clinical isolates of Escherichia coli and Klebsiella pneumoniae in Sydney, Australia, where we also found one example of bla(CTX-M-62), encoding a novel enzyme conferring ceftazidime resistance. ESBL genes were present in diverse community isolates and in a variety of associated conjugative plasmids.

SUBMITTER: Zong Z

PROVIDER: S-EPMC2573124 | biostudies-literature | 2008 Nov

REPOSITORIES: biostudies-literature

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Dominance of blaCTX-M within an Australian extended-spectrum beta-lactamase gene pool.

Zong Zhiyong Z Partridge Sally R SR Thomas Lee L Iredell Jonathan R JR

Antimicrobial agents and chemotherapy 20080825 11

bla(CTX-M) genes, particularly bla(CTX-M-15), are the dominant extended-spectrum beta-lactamase (ESBL) genes among clinical isolates of Escherichia coli and Klebsiella pneumoniae in Sydney, Australia, where we also found one example of bla(CTX-M-62), encoding a novel enzyme conferring ceftazidime resistance. ESBL genes were present in diverse community isolates and in a variety of associated conjugative plasmids. ...[more]

PMID: 18725449

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