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Identification of genes encoding the folate- and thiamine-binding membrane proteins in Firmicutes.

ABSTRACT: Genes encoding high-affinity folate- and thiamine-binding proteins (FolT, ThiT) were identified in the Lactobacillus casei genome, expressed in Lactococcus lactis, and functionally characterized. Similar genes occur in many Firmicutes, sometimes next to folate or thiamine salvage genes. Most thiT genes are preceded by a thiamine riboswitch.

SUBMITTER: Eudes A

PROVIDER: S-EPMC2576666 | biostudies-literature | 2008 Nov

REPOSITORIES: biostudies-literature

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Identification of genes encoding the folate- and thiamine-binding membrane proteins in Firmicutes.

Eudes Aymerick A Erkens Guus B GB Slotboom Dirk J DJ Rodionov Dmitry A DA Naponelli Valeria V Hanson Andrew D AD

Journal of bacteriology 20080905 22

Genes encoding high-affinity folate- and thiamine-binding proteins (FolT, ThiT) were identified in the Lactobacillus casei genome, expressed in Lactococcus lactis, and functionally characterized. Similar genes occur in many Firmicutes, sometimes next to folate or thiamine salvage genes. Most thiT genes are preceded by a thiamine riboswitch. ...[more]

PMID: 18776013

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