Ontology highlight
ABSTRACT:
SUBMITTER: Mao P
PROVIDER: S-EPMC2582219 | biostudies-literature | 2007 Aug
REPOSITORIES: biostudies-literature
Mao Peizhong P Ardeshiri Ardi A Jacks Rachel R Yang Sufang S Hurn Patricia D PD Alkayed Nabil J NJ
The European journal of neuroscience 20070718 3
We previously demonstrated that the neuropeptide cocaine- and amphetamine-regulated transcript (CART) is protective against focal cerebral ischemia in vivo and against neuronal cell death in culture induced by oxygen-glucose deprivation (OGD). The mechanism of neuroprotection by CART is unknown, in part due to lack of knowledge regarding its putative receptor. Using a yeast two-hybrid system with CART's carboxy-terminal to screen a mouse brain cDNA library, we uncovered a potential direct intera ...[more]