Ontology highlight
ABSTRACT:
SUBMITTER: Blinder P
PROVIDER: S-EPMC2582457 | biostudies-literature | 2008
REPOSITORIES: biostudies-literature
Blinder Pablo P Cove Joshua J Foox Maytal M Baranes Danny D
PloS one 20081121 11
The manner by which axons distribute synaptic connections along dendrites remains a fundamental unresolved issue in neuronal development and physiology. We found in vitro and in vivo indications that dendrites determine the density, location and strength of their synaptic inputs by controlling the distance of their branches from those of their neighbors. Such control occurs through collective branch convergence, a behavior promoted by AMPA and NMDA glutamate receptor activity. At hubs of converg ...[more]