Ontology highlight
ABSTRACT:
SUBMITTER: Reichert VL
PROVIDER: S-EPMC2583179 | biostudies-literature | 2007 Jul
REPOSITORIES: biostudies-literature
Reichert Vienna L VL Choi Mehee M Petrillo Jessica E JE Gehrke Lee L
Virology 20070402 1
Alfalfa mosaic virus (AMV) RNA replication requires the viral coat protein (CP). AMV CP is an integral component of the viral replicase; moreover, it binds to the viral RNA 3'-termini and induces the formation of multiple new base pairs that organize the RNA conformation. The results described here suggest that AMV coat protein binding defines template selection by organizing the 3'-terminal RNA conformation and by positioning the RNA-dependent RNA polymerase (RdRp) at the initiation site for mi ...[more]