Ontology highlight
ABSTRACT:
SUBMITTER: Kleine-Vehn J
PROVIDER: S-EPMC2584678 | biostudies-literature | 2008 Nov
REPOSITORIES: biostudies-literature
Kleine-Vehn Jürgen J Leitner Johannes J Zwiewka Marta M Sauer Michael M Abas Lindy L Luschnig Christian C Friml Jirí J
Proceedings of the National Academy of Sciences of the United States of America 20081112 46
All eukaryotic cells present at the cell surface a specific set of plasma membrane proteins that modulate responses to internal and external cues and whose activity is also regulated by protein degradation. We characterized the lytic vacuole-dependent degradation of membrane proteins in Arabidopsis thaliana by means of in vivo visualization of vacuolar targeting combined with quantitative protein analysis. We show that the vacuolar targeting pathway is used by multiple cargos including PIN-FORME ...[more]