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Optimal TBHP allylic oxidation of Delta5-steroids catalyzed by dirhodium caprolactamate.

ABSTRACT: Dirhodium caprolactamate is the most efficient catalyst for the oxidation of Delta5-steroids to 7-keto-Delta5-steroids by 70% tert-butyl hydroperoxide in water (T-HYDRO). Isolated product yields range from 38 to 87%.

SUBMITTER: Choi H

PROVIDER: S-EPMC2596589 | biostudies-literature | 2007 Dec

REPOSITORIES: biostudies-literature

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Optimal TBHP allylic oxidation of Delta5-steroids catalyzed by dirhodium caprolactamate.

Choi Hojae H Doyle Michael P MP

Organic letters 20071121 26

Dirhodium caprolactamate is the most efficient catalyst for the oxidation of Delta5-steroids to 7-keto-Delta5-steroids by 70% tert-butyl hydroperoxide in water (T-HYDRO). Isolated product yields range from 38 to 87%. ...[more]

PMID: 18027961

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