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Chemoselective Three-Component Coupling via A Tandem Pd Catalyzed Boron-Heck and Suzuki Reaction.

ABSTRACT: Reported herein is a new approach to prepare biaryl derivatives via a tandem Pd catalyzed boron-Heck and Suzuki reaction. This one-pot tandem process avoided purification or addition of extra catalyst between steps. The resulting biaryl compounds can be prepared with substrate variability in good to moderate yields.

SUBMITTER: O'Neill J 

PROVIDER: S-EPMC2598413 | biostudies-literature | 2008 Dec

REPOSITORIES: biostudies-literature

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Chemoselective Three-Component Coupling via A Tandem Pd Catalyzed Boron-Heck and Suzuki Reaction.

O'Neill Justin J   Yoo Kyung Soo KS   Jung Kyung Woon KW  

Tetrahedron letters 20081201 51

Reported herein is a new approach to prepare biaryl derivatives via a tandem Pd catalyzed boron-Heck and Suzuki reaction. This one-pot tandem process avoided purification or addition of extra catalyst between steps. The resulting biaryl compounds can be prepared with substrate variability in good to moderate yields. ...[more]

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