Ontology highlight
ABSTRACT:
SUBMITTER: Lv J
PROVIDER: S-EPMC2605842 | biostudies-literature | 2008 Jul
REPOSITORIES: biostudies-literature
Lv Juanxiu J Mao Caiping C Zhu Liyan L Zhang Hong H Pengpeng Hui H Xu Feichao F Liu Yujuan Y Zhang Lubo L Xu Zhice Z
Neurotoxicology 20080502 4
Previous studies have suggested that prenatal exposure to nicotine is associated with abnormal development in fetuses, including fetal brain damage. The present study determined the effect of maternal administration of nicotine during different gestational periods on brain nicotine receptor subunits in fetal rats. Subcutaneous injections of nicotine in maternal rats from the early and middle gestation decreased fetal blood PO2, increased fetal blood PCO2 and hemoglobin, and decreased fetal brain ...[more]