Unknown

Dataset Information

0

Novel approach to multifunctionalized homoallylic alcohols via regioselective ring opening of aryl oxiranes with 3-iodo allenoates.


ABSTRACT: [reaction: see text] 3-Iodo allenoates were generated in situ and utilized, for the first time, in the ring opening of oxiranes in a regioselective fashion. This simple one-pot three-component reaction protocol provides easy access to highly functionalized homoallylic alcohols in good yields and moderate to very good (Z/E) selectivity. The two functional groups (ester and halogen) can be further subjected to many synthetic transformations.

SUBMITTER: Kattuboina A 

PROVIDER: S-EPMC2613809 | biostudies-literature | 2006 Jun

REPOSITORIES: biostudies-literature

altmetric image

Publications

Novel approach to multifunctionalized homoallylic alcohols via regioselective ring opening of aryl oxiranes with 3-iodo allenoates.

Kattuboina Adiseshu A   Kaur Parminder P   Timmons Cody C   Li Guigen G  

Organic letters 20060601 13


[reaction: see text] 3-Iodo allenoates were generated in situ and utilized, for the first time, in the ring opening of oxiranes in a regioselective fashion. This simple one-pot three-component reaction protocol provides easy access to highly functionalized homoallylic alcohols in good yields and moderate to very good (Z/E) selectivity. The two functional groups (ester and halogen) can be further subjected to many synthetic transformations. ...[more]

Similar Datasets

| S-EPMC4333593 | biostudies-literature
| S-EPMC4930112 | biostudies-literature
| S-EPMC5082584 | biostudies-literature
| S-EPMC7116117 | biostudies-literature
| S-EPMC6014093 | biostudies-literature
| S-EPMC7508174 | biostudies-literature
| S-EPMC8297733 | biostudies-literature
| S-EPMC3096926 | biostudies-literature
| S-EPMC9064361 | biostudies-literature
| S-EPMC6269844 | biostudies-literature