Ontology highlight
ABSTRACT:
SUBMITTER: Kattuboina A
PROVIDER: S-EPMC2613809 | biostudies-literature | 2006 Jun
REPOSITORIES: biostudies-literature
Kattuboina Adiseshu A Kaur Parminder P Timmons Cody C Li Guigen G
Organic letters 20060601 13
[reaction: see text] 3-Iodo allenoates were generated in situ and utilized, for the first time, in the ring opening of oxiranes in a regioselective fashion. This simple one-pot three-component reaction protocol provides easy access to highly functionalized homoallylic alcohols in good yields and moderate to very good (Z/E) selectivity. The two functional groups (ester and halogen) can be further subjected to many synthetic transformations. ...[more]