Ontology highlight
ABSTRACT:
SUBMITTER: Ebersbach G
PROVIDER: S-EPMC2614312 | biostudies-literature | 2008 Sep
REPOSITORIES: biostudies-literature
Ebersbach Gitte G Briegel Ariane A Jensen Grant J GJ Jacobs-Wagner Christine C
Cell 20080901 6
Cell polarization is an integral part of many unrelated bacterial processes. How intrinsic cell polarization is achieved is poorly understood. Here, we provide evidence that Caulobacter crescentus uses a multimeric pole-organizing factor (PopZ) that serves as a hub to concurrently achieve several polarizing functions. During chromosome segregation, polar PopZ captures the ParB*ori complex and thereby anchors sister chromosomes at opposite poles. This step is essential for stabilizing bipolar gra ...[more]