Ontology highlight
ABSTRACT:
SUBMITTER: Ernkvist M
PROVIDER: S-EPMC2614636 | biostudies-literature | 2009 Jan
REPOSITORIES: biostudies-literature
Ernkvist Mira M Luna Persson Nathalie N Audebert Stéphane S Lecine Patrick P Sinha Indranil I Liu Miaoliang M Schlueter Marc M Horowitz Arie A Aase Karin K Weide Thomas T Borg Jean-Paul JP Majumdar Arindam A Holmgren Lars L
Blood 20080929 1
Controlled regulation of Rho GTPase activity is an essential component mediating growth factor-stimulated migration. We have previously shown that angiomotin (Amot), a membrane-associated scaffold protein, plays a critical role during vascular patterning and endothelial migration during embryogenesis. However, the signaling pathways by which Amot controls directional migration are not known. Here we have used peptide pull-down and yeast 2-hybrid (Y2H) screening to identify proteins that interact ...[more]