Ontology highlight
ABSTRACT:
SUBMITTER: Paczesny S
PROVIDER: S-EPMC2615645 | biostudies-literature | 2009 Jan
REPOSITORIES: biostudies-literature
Paczesny Sophie S Krijanovski Oleg I OI Braun Thomas M TM Choi Sung W SW Clouthier Shawn G SG Kuick Rork R Misek David E DE Cooke Kenneth R KR Kitko Carrie L CL Weyand Angela A Bickley Daniel D Jones Dawn D Whitfield Joel J Reddy Pavan P Levine John E JE Hanash Samir M SM Ferrara James L M JL
Blood 20081002 2
No validated biomarkers exist for acute graft-versus-host disease (GVHD). We screened plasma with antibody microarrays for 120 proteins in a discovery set of 42 patients who underwent transplantation that revealed 8 potential biomarkers for diagnostic of GVHD. We then measured by enzyme-linked immunosorbent assay (ELISA) the levels of these biomarkers in samples from 424 patients who underwent transplantation randomly divided into training (n = 282) and validation (n = 142) sets. Logistic regres ...[more]