Ontology highlight
ABSTRACT:
SUBMITTER: Curanovic D
PROVIDER: S-EPMC2620901 | biostudies-literature | 2009 Feb
REPOSITORIES: biostudies-literature
Curanović D D Lyman M G MG Bou-Abboud C C Card J P JP Enquist L W LW
Journal of virology 20081119 3
The attenuated pseudorabies virus (PRV) strain Bartha contains several characterized mutations that affect its virulence and ability to spread through neural circuits. This strain contains a small genomic deletion that abrogates anterograde spread and is widely used as a retrograde-restricted neural circuit tracer. Previous studies showed that the retrograde-directed spread of PRV Bartha is slower than that of wild-type PRV. We used compartmented neuronal cultures to characterize the retrograde ...[more]