Ontology highlight
ABSTRACT:
SUBMITTER: Blauvelt ML
PROVIDER: S-EPMC2628538 | biostudies-literature | 2008 Dec
REPOSITORIES: biostudies-literature
Blauvelt Marisa L ML Khalili Maryam M Jaung Weonjoo W Paulsen Janet J Anderson Amy C AC Brian Wilson S S Howell Amy R AR
Bioorganic & medicinal chemistry letters 20081101 24
The synthesis and evaluation for iNKT stimulation of alpha-S-galactosylceramide is reported. Prepared by alkylation of a galactosylthiol, this analog of the potent immunostimulatory agent, KRN7000, did not stimulate iNKT cells either in vitro or in vivo. ...[more]