Ontology highlight
ABSTRACT:
SUBMITTER: Yen-Revollo JL
PROVIDER: S-EPMC2632586 | biostudies-literature | 2008 Nov
REPOSITORIES: biostudies-literature
Yen-Revollo Jane L JL Auman J Todd JT McLeod Howard L HL
Pharmacogenomics 20081101 11
<h4>Introduction</h4>Polymorphic alleles in the human genome have been identified as affecting numerous drug responses. Currently, genotyping of all patients before starting a drug regimen is impractical. Since many polymorphisms occur at varying rates in different racial groups, we investigated whether a patient's race could predict presence of drug-relevant genetic variants well enough to be used as a substitute for individual genotyping.<h4>Methods</h4>We performed hierarchical clustering and ...[more]