Ontology highlight
ABSTRACT:
SUBMITTER: Monteiro MA
PROVIDER: S-EPMC2643618 | biostudies-literature | 2009 Mar
REPOSITORIES: biostudies-literature
Monteiro Mario A MA Baqar Shahida S Hall Eric R ER Chen Yu-Han YH Porter Chad K CK Bentzel David E DE Applebee Lisa L Guerry Patricia P
Infection and immunity 20081229 3
The capsule polysaccharide (CPS) of Campylobacter jejuni is one of the few identified virulence determinants of this important human pathogen. Since CPS conjugate vaccines have been so effective against other mucosal pathogens, we evaluated this approach using CPSs from two strains of C. jejuni, 81-176 (HS23 and HS36 serotype complex) and CG8486 (HS4 serotype complex). The CPSs of 81-176 and CG8486 were independently linked to the carrier protein CRM(197) by reductive amination between an aldehy ...[more]