Core promoters are predicted by their distinct physicochemical properties in the genome of Plasmodium falciparum.
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ABSTRACT:
SUBMITTER: Brick K
PROVIDER: S-EPMC2646282 | biostudies-literature | 2008
REPOSITORIES: biostudies-literature
Publications
Core promoters are predicted by their distinct physicochemical properties in the genome of Plasmodium falciparum.
Brick Kevin K Watanabe Junichi J Pizzi Elisabetta E
Genome biology 20081218 12
Little is known about the structure and distinguishing features of core promoters in Plasmodium falciparum. In this work, we describe the first method to computationally identify core promoters in this AT-rich genome. This prediction algorithm uses solely DNA physicochemical properties as descriptors. Our results add to a growing body of evidence that a physicochemical code for eukaryotic genomes plays a crucial role in core promoter recognition. ...[more]
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