Ontology highlight
ABSTRACT:
SUBMITTER: Araujo RBD
PROVIDER: S-EPMC6008437 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Araujo Rosana Beatriz Duque RBD Silva Tatiane Macedo TM Kaiser Charlotte Sophie CS Leite Gabriela Fernandes GF Alonso Diego D Ribolla Paulo Eduardo Martins PEM Wunderlich Gerhard G
Scientific reports 20180619 1
All Plasmodium species express variant antigens which may mediate immune escape in the vertebrate host. In Plasmodium falciparum, the rif gene family encodes variant antigens which are partly exposed on the infected red blood cell surface and may function as virulence factors. Not all rif genes are expressed at the same time and it is unclear what controls rif gene expression. In this work, we addressed global rif transcription using plasmid vectors with two drug resistance markers, one controll ...[more]