KEGG spider: interpretation of genomics data in the context of the global gene metabolic network.
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ABSTRACT:
SUBMITTER: Antonov AV
PROVIDER: S-EPMC2646283 | biostudies-literature | 2008
REPOSITORIES: biostudies-literature
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KEGG spider: interpretation of genomics data in the context of the global gene metabolic network.
Antonov Alexey V AV Dietmann Sabine S Mewes Hans W HW
Genome biology 20081218 12
KEGG spider is a web-based tool for interpretation of experimentally derived gene lists in order to gain understanding of metabolism variations at a genomic level. KEGG spider implements a 'pathway-free' framework that overcomes a major bottleneck of enrichment analyses: it provides global models uniting genes from different metabolic pathways. Analyzing a number of experimentally derived gene lists, we demonstrate that KEGG spider provides deeper insights into metabolism variations in compariso ...[more]
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