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Synthetic "chaperones": nanoparticle-mediated refolding of thermally denatured proteins.


ABSTRACT: Thermally denatured chymotrypsin, lysozyme and papain are substantially refolded towards their native conformation by gold nanoparticle bearing dicarboxylate sidechains.

SUBMITTER: De M 

PROVIDER: S-EPMC2646367 | biostudies-literature | 2008 Aug

REPOSITORIES: biostudies-literature

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Synthetic "chaperones": nanoparticle-mediated refolding of thermally denatured proteins.

De Mrinmoy M   Rotello Vincent M VM  

Chemical communications (Cambridge, England) 20080523 30


Thermally denatured chymotrypsin, lysozyme and papain are substantially refolded towards their native conformation by gold nanoparticle bearing dicarboxylate sidechains. ...[more]

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