Ontology highlight
ABSTRACT:
SUBMITTER: Antonara S
PROVIDER: S-EPMC2651023 | biostudies-literature | 2007 Oct
REPOSITORIES: biostudies-literature
Antonara Styliani S Chafel Rebecca M RM LaFrance Michelle M Coburn Jenifer J
Molecular microbiology 20070903 1
Borrelia burgdorferi, the agent of Lyme disease, disseminates from the site of deposition by Ixodes ticks to cause systemic infection. Dissemination occurs through the circulation and through tissue matrices, but the B. burgdorferi molecules that mediate interactions with the endothelium in vivo have not yet been identified. In vivo selection of filamentous phage expressing B. burgdorferi protein fragments on the phage surface identified several new candidate adhesins, and verified the activity ...[more]