Ontology highlight
ABSTRACT:
SUBMITTER: Riley SP
PROVIDER: S-EPMC2665219 | biostudies-literature | 2009 Apr
REPOSITORIES: biostudies-literature
Nucleic acids research 20090210 6
The Lyme disease spirochete, Borrelia burgdorferi, encodes a novel type of DNA-binding protein named EbfC. Orthologs of EbfC are encoded by a wide range of bacterial species, so characterization of the borrelial protein has implications that span the eubacterial kingdom. The present work defines the DNA sequence required for high-affinity binding by EbfC to be the 4 bp broken palindrome GTnAC, where 'n' can be any nucleotide. Two high-affinity EbfC-binding sites are located immediately 5' of B. ...[more]