Ontology highlight
ABSTRACT:
SUBMITTER: McMullen CA
PROVIDER: S-EPMC2657173 | biostudies-literature | 2009 Apr
REPOSITORIES: biostudies-literature
The journals of gerontology. Series A, Biological sciences and medical sciences 20090217 4
Laryngeal muscle dysfunction compromises voice, swallowing, and airway protection in elderly adults. Laryngeal muscles and their motor neurons and their motor neurons communicate via the neuromuscular junction (NMJ). We tested the hypothesis that aging disrupts NMJ organization and function in the laryngeal thyroarytenoid (TA) and posterior cricoarytenoid (PCA) muscles We determined NMJ density and size and acetylcholine receptor (AChR) subunit mRNAs in TA and PCA muscles from 6-, 18-, and 30- m ...[more]