Ontology highlight
ABSTRACT:
SUBMITTER: Kroeger TS
PROVIDER: S-EPMC2657376 | biostudies-literature | 2009 Mar
REPOSITORIES: biostudies-literature
Kroeger Tiffany S TS Watkins Kenneth P KP Friso Giulia G van Wijk Klaas J KJ Barkan Alice A
Proceedings of the National Academy of Sciences of the United States of America 20090226 11
Comparative genomics has provided evidence for numerous conserved protein domains whose functions remain unknown. We identified a protein harboring "domain of unknown function 860" (DUF860) as a component of group II intron ribonucleoprotein particles in maize chloroplasts. This protein, assigned the name WTF1 ("what's this factor?"), coimmunoprecipitates from chloroplast extract with group II intron RNAs, is required for the splicing of the introns with which it associates, and promotes splicin ...[more]