Ontology highlight
ABSTRACT:
SUBMITTER: Hosler JP
PROVIDER: S-EPMC2659341 | biostudies-literature | 2006
REPOSITORIES: biostudies-literature
Hosler Jonathan P JP Ferguson-Miller Shelagh S Mills Denise A DA
Annual review of biochemistry 20060101
A series of metalloprotein complexes embedded in a mitochondrial or bacterial membrane utilize electron transfer reactions to pump protons across the membrane and create an electrochemical potential (DeltamuH+). Current understanding of the principles of electron-driven proton transfer is discussed, mainly with respect to the wealth of knowledge available from studies of cytochrome c oxidase. Structural, experimental, and theoretical evidence supports the model of long-distance proton transfer v ...[more]