A unifying nitrososynthase involved in nitrosugar biosynthesis.
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ABSTRACT:
SUBMITTER: Hu Y
PROVIDER: S-EPMC2661260 | biostudies-literature | 2008 Nov
REPOSITORIES: biostudies-literature
Publications
A unifying nitrososynthase involved in nitrosugar biosynthesis.
Hu Yunfeng Y Al-Mestarihi Ahmad A Grimes Catherine L CL Kahne Daniel D Bachmann Brian O BO
Journal of the American Chemical Society 20081101 47
Herein we describe the cloning, functional expression and initial characterization of ORF36 from Micromonospora carbonacae var. africana and rubN8 from Streptomyces achromogenes var. rubradiris. The purified enzymes play the same role, the double-oxidation of TDP-evernosamine to TDP-evernitrosose in the everninomycin and rubradirin pathways, respectively. ...[more]
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