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Metallic nanohole arrays on fluoropolymer substrates as small label-free real-time bioprobes.

ABSTRACT: We describe a nanoplasmonic probing platform that exploits small-dimension (

SUBMITTER: Yang JC

PROVIDER: S-EPMC2662724 | biostudies-literature | 2008 Sep

REPOSITORIES: biostudies-literature

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Metallic nanohole arrays on fluoropolymer substrates as small label-free real-time bioprobes.

Yang Jiun-Chan JC Ji Jin J Hogle James M JM Larson Dale N DN

Nano letters 20080819 9

We describe a nanoplasmonic probing platform that exploits small-dimension (<or=20 microm (2)) ordered arrays of subwavelength holes for multiplexed, high spatial resolution, and real-time analysis on biorecognition events. Nanohole arrays are perforated on a super smooth gold surface (roughness rms < 2.7 A) attached on a fluoropolymer (FEP) substrate fabricated by a replica technique. The smooth surface of gold provides a superb environment for fabricating nanometer features and uniform immobil ...[more]

PMID: 18710296

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