Ontology highlight
ABSTRACT:
SUBMITTER: Nash KA
PROVIDER: S-EPMC2663066 | biostudies-literature | 2009 Apr
REPOSITORIES: biostudies-literature
Nash Kevin A KA Brown-Elliott Barbara A BA Wallace Richard J RJ
Antimicrobial agents and chemotherapy 20090126 4
Mycobacterium abscessus infections tend to respond poorly to macrolide-based chemotherapy, even though the organisms appear to be susceptible to clarithromycin. Circumstantial evidence suggested that at least some M. abscessus isolates might be inducibly resistant to macrolides. Thus, the purpose of this study was to investigate the macrolide phenotype of M. abscessus clinical isolates. Inducible resistance to clarithromycin (MIC > 32 microg/ml) was found for 7 of 10 clinical isolates of M. absc ...[more]