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Gold-Speckled Multimodal Nanoparticles for Noninvasive Bioimaging.

ABSTRACT: Multimodal Gold-speckled silica nanoparticles as contrast agents for noninvasive imaging with magnetic resonance imaging and photoacoustic tomography have been prepared in a simple one-pot synthesis using nonionic microemulsions. Magnetic resonance contrast is provided through gadolinium incorporated in the silica matrix, whereas the photoacoustic signal originates from nonuniform, discontinuous gold nanodomains speckled across the silica surface.

SUBMITTER: Sharma P

PROVIDER: S-EPMC2664628 | biostudies-literature | 2008 Oct

REPOSITORIES: biostudies-literature

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Gold-Speckled Multimodal Nanoparticles for Noninvasive Bioimaging.

Sharma Parvesh P Brown Scott C SC Bengtsson Niclas N Zhang Qizhi Q Walter Glenn A GA Grobmyer Stephen R SR Santra Swadeshmukul S Jiang Huabei H Scott Edward W EW Moudgil Brij M BM

Chemistry of materials : a publication of the American Chemical Society 20080912 19

Multimodal Gold-speckled silica nanoparticles as contrast agents for noninvasive imaging with magnetic resonance imaging and photoacoustic tomography have been prepared in a simple one-pot synthesis using nonionic microemulsions. Magnetic resonance contrast is provided through gadolinium incorporated in the silica matrix, whereas the photoacoustic signal originates from nonuniform, discontinuous gold nanodomains speckled across the silica surface. ...[more]

PMID: 19466201

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