CD4+ T cell depletion in an untreated HIV type 1-infected human leukocyte antigen-B*5801-positive patient with an undetectable viral load.
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ABSTRACT:
SUBMITTER: Andrade A
PROVIDER: S-EPMC2664682 | biostudies-literature | 2008 Apr
REPOSITORIES: biostudies-literature
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CD4+ T cell depletion in an untreated HIV type 1-infected human leukocyte antigen-B*5801-positive patient with an undetectable viral load.
Andrade Adriana A Bailey Justin R JR Xu Jie J Philp Frances H FH Quinn Thomas C TC Williams Thomas M TM Ray Stuart C SC Thomas David L DL Blankson Joel N JN
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20080401 8
We report a case of a patient infected with human immunodeficiency virus type 1 (HIV-1) for 20 years who has experienced CD4(+) T cell depletion in spite of maintaining undetectable viral loads. Our data suggest that immune activation can cause CD4(+) T cell depletion even when HIV-1 replication appears to be controlled by host factors. ...[more]
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