Ontology highlight
ABSTRACT:
SUBMITTER: Trost BM
PROVIDER: S-EPMC2665030 | biostudies-literature | 2008 Nov
REPOSITORIES: biostudies-literature
Trost Barry M BM McDougall Patrick J PJ Hartmann Olaf O Wathen Peter T PT
Journal of the American Chemical Society 20081021 45
The cyanosubstituted trimethylenemethane donor undergoes palladium-catalyzed [6 + 3] cycloaddition with a variety of tropones to yield bicyclo[4.3.1]decadienes in excellent regio-, diastereo-, and enantioselectivity. Products of the Pd-TMM [6 + 3] cycloaddition participate in a thermal [3,3] sigmatropic rearrangement to yield bicyclo[3.3.2]decadienes in good yield. ...[more]