Ontology highlight
ABSTRACT:
SUBMITTER: Romagnoli S
PROVIDER: S-EPMC2665738 | biostudies-literature | 2009 Mar
REPOSITORIES: biostudies-literature
Romagnoli Solange S Fasoli Ester E Vaira Valentina V Falleni Monica M Pellegrini Caterina C Catania Anna A Roncalli Massimo M Marchetti Antonio A Santambrogio Luigi L Coggi Guido G Bosari Silvano S
The American journal of pathology 20090213 3
Cell-cycle defects are responsible for cancer onset and growth. We studied the expression profile of 60 genes involved in cell cycle in a series of malignant mesotheliomas (MMs), normal pleural tissues, and MM cell cultures using a quantitative polymerase chain reaction-based, low-density array. Nine genes were significantly deregulated in MMs compared with normal controls. Seven genes were overexpressed in MMs, including the following: CDKN2C, cdc6, cyclin H, cyclin B1, CDC2, FoxM1, and Chk1, w ...[more]