Ontology highlight
ABSTRACT:
SUBMITTER: Tadpetch K
PROVIDER: S-EPMC2665917 | biostudies-literature | 2008 Nov
REPOSITORIES: biostudies-literature
Organic letters 20080925 21
The rhenium(VII) complex O3ReOSiPh3 is a particularly effective catalyst for Prins cyclizations using aromatic and alpha,beta-unsaturated aldehydes. The reaction conditions are mild, and the highly substituted 4-hydroxytetrahydropyran products are formed stereoselectively. Rhenium(VII) complexes appear to spontaneously form esters with alcohols and to directly activate electron-rich alcohols for solvolysis. Re2O7 and perrhenic acid are equally effective in catalyzing these cyclizations. ...[more]