Unknown

Dataset Information

0

Male-pattern baldness susceptibility locus at 20p11.

ABSTRACT: We conducted a genome-wide association study for androgenic alopecia in 1,125 men and identified a newly associated locus at chromosome 20p11.22, confirmed in three independent cohorts (n = 1,650; OR = 1.60, P = 1.1 x 10(-14) for rs1160312). The one man in seven who harbors risk alleles at both 20p11.22 and AR (encoding the androgen receptor) has a sevenfold-increased odds of androgenic alopecia (OR = 7.12, P = 3.7 x 10(-15)).

SUBMITTER: Richards JB 

PROVIDER: S-EPMC2672151 | biostudies-literature | 2008 Nov

REPOSITORIES: biostudies-literature

Json Xml
altmetric image

Publications

We conducted a genome-wide association study for androgenic alopecia in 1,125 men and identified a newly associated locus at chromosome 20p11.22, confirmed in three independent cohorts (n = 1,650; OR = 1.60, P = 1.1 x 10(-14) for rs1160312). The one man in seven who harbors risk alleles at both 20p11.22 and AR (encoding the androgen receptor) has a sevenfold-increased odds of androgenic alopecia (OR = 7.12, P = 3.7 x 10(-15)). ...[more]

Similar Datasets

Unknown Genetic prediction of male pattern baldness.
| S-EPMC5308812 | biostudies-literature
Unknown Prediction of male-pattern baldness from genotypes.
| S-EPMC4867459 | biostudies-literature
Unknown GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk.
| S-EPMC5691155 | biostudies-literature
Unknown Dissection of genetic variation and evidence for pleiotropy in male pattern baldness.
| S-EPMC6302097 | biostudies-literature
Unknown Male pattern baldness and its association with coronary heart disease: a meta-analysis.
| S-EPMC3641488 | biostudies-literature
Unknown Evidence for a functional interaction of WNT10A and EBF1 in male-pattern baldness.
| S-EPMC8432770 | biostudies-literature
Unknown Male pattern baldness and risk of incident skin cancer in a cohort of men.
| S-EPMC5061600 | biostudies-literature
Genomics Genome-wide association data on male-pattern baldness
| EGAS00001001354 | EGA
Unknown Evaluation of DNA variants associated with androgenetic alopecia and their potential to predict male pattern baldness.
| S-EPMC4441445 | biostudies-literature
Unknown Male-pattern baldness and incident coronary heart disease and risk factors in the Heinz Nixdorf Recall Study.
| S-EPMC6863534 | biostudies-literature