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Spontaneous quinolone resistance in the zoonotic serovar of Vibrio vulnificus.

ABSTRACT: This work demonstrates that Vibrio vulnificus biotype 2, serovar E, an eel pathogen able to infect humans, can become resistant to quinolone by specific mutations in gyrA (substitution of isoleucine for serine at position 83) and to some fluoroquinolones by additional mutations in parC (substitution of lysine for serine at position 85). Thus, to avoid the selection of resistant strains that are potentially pathogenic for humans, antibiotics other than quinolones must be used to treat vibriosis on farms.

SUBMITTER: Roig FJ

PROVIDER: S-EPMC2675197 | biostudies-literature | 2009 Apr

REPOSITORIES: biostudies-literature

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Spontaneous quinolone resistance in the zoonotic serovar of Vibrio vulnificus.

Roig Francisco J FJ Llorens A A Fouz B B Amaro C C

Applied and environmental microbiology 20090213 8

This work demonstrates that Vibrio vulnificus biotype 2, serovar E, an eel pathogen able to infect humans, can become resistant to quinolone by specific mutations in gyrA (substitution of isoleucine for serine at position 83) and to some fluoroquinolones by additional mutations in parC (substitution of lysine for serine at position 85). Thus, to avoid the selection of resistant strains that are potentially pathogenic for humans, antibiotics other than quinolones must be used to treat vibriosis o ...[more]

PMID: 19218407

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2022-02-18 | GSE196944 | GEO

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Vibrio vulnificus biotype 2 serovar E gne but not galE is essential for lipopolysaccharide biosynthesis and virulence.

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Isolation of Vibrio vulnificus from Seawater and Emerging Vibrio vulnificus Septicemia on Jeju Island.

Project description:Vibrio vulnificus is an opportunistic human pathogen, transmitted from seawater, raw oyster, and shellfish and responsible for severe septicemia. We studied V. vulnificus from surface seawater around Jeju Island between 2010 and 2011. In 2010, V. vulnificus was isolated and V. vulnificus septicemia was reported. Surface seawater temperature is an important factor for growth of V. vulnificus, and here we showed that high surface seawater temperature may influence growth of V. vulnificus and occurrence of emerging V. vulnificus septicemia on Jeju Island. This is the first report of isolation of V. vulnificus and emerging V. vulnificus septicemia on Jeju Island.

| S-EPMC4091370 | biostudies-literature

Quinolone Resistance Genes and Their Contribution to Resistance in <i>Vibrio cholerae</i> Serogroup O139.

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| S-EPMC9952142 | biostudies-literature

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