Ontology highlight
ABSTRACT:
SUBMITTER: Ahn J
PROVIDER: S-EPMC2675652 | biostudies-literature | 2009 May
REPOSITORIES: biostudies-literature
Ahn Jiyoung J Albanes Demetrius D Berndt Sonja I SI Peters Ulrike U Chatterjee Nilanjan N Freedman Neal D ND Abnet Christian C CC Huang Wen-Yi WY Kibel Adam S AS Crawford E David ED Weinstein Stephanie J SJ Chanock Stephen J SJ Schatzkin Arthur A Hayes Richard B RB
Carcinogenesis 20090302 5
We systematically investigated the association of 48 SNPS in four vitamin D metabolizing genes [CYP27A1, GC, CYP27B1 and CYP24A1] with serum 25-hydroxyvitamin D [25(OH)D] and 1,25-dihydroxyvitamin D [1,25(OH)(2)D] levels and the association of these SNPS and an additional 164 SNPS in eight downstream mediators of vitamin D signaling [VDR, RXRA, RXRB, PPAR, NCOA1, NCOA2, NCOA3 and SMAD3] with prostate cancer risk in the 749 incident prostate cancer cases and 781 controls of the Prostate, Lung, Co ...[more]