Ontology highlight
ABSTRACT:
SUBMITTER: Korkhin Y
PROVIDER: S-EPMC2675907 | biostudies-literature | 2009 May
REPOSITORIES: biostudies-literature
Korkhin Yakov Y Unligil Ulug M UM Littlefield Otis O Nelson Pamlea J PJ Stuart David I DI Sigler Paul B PB Bell Stephen D SD Abrescia Nicola G A NG
PLoS biology 20090505 5
The archaeal RNA polymerase (RNAP) shares structural similarities with eukaryotic RNAP II but requires a reduced subset of general transcription factors for promoter-dependent initiation. To deepen our knowledge of cellular transcription, we have determined the structure of the 13-subunit DNA-directed RNAP from Sulfolobus shibatae at 3.35 Å resolution. The structure contains the full complement of subunits, including RpoG/Rpb8 and the equivalent of the clamp-head and jaw domains of the eukaryoti ...[more]