Ontology highlight
ABSTRACT:
SUBMITTER: Rivera-Lopez CM
PROVIDER: S-EPMC2677190 | biostudies-literature | 2008
REPOSITORIES: biostudies-literature
Rivera-Lopez Carol M CM Tucker Amy L AL Lynch Kevin R KR
Angiogenesis 20080527 3
Lysophosphatidic acid (LPA) is a simple lipid with many important biological functions such as the regulation of cellular proliferation, cellular migration, differentiation, and suppression of apoptosis. Although a direct angiogenic effect of LPA has not been reported to date, there are indications that LPA promotes angiogenesis. In addition, LPA is a chemoattractant for cultured endothelial cells and promotes barrier function in such cultures. To test the hypothesis that LPA is angiogenic, we u ...[more]