Ontology highlight
ABSTRACT:
SUBMITTER: Wang PY
PROVIDER: S-EPMC2678437 | biostudies-literature | 2009 Apr
REPOSITORIES: biostudies-literature
Wang Pei-Yu PY Protheroe Anna A Clarkson Andrew N AN Imhoff Floriane F Koishi Kyoko K McLennan Ian S IS
Proceedings of the National Academy of Sciences of the United States of America 20090409 17
Many behavioral traits and most brain disorders are common to males and females but are more evident in one sex than the other. The control of these subtle sex-linked biases is largely unstudied and has been presumed to mirror that of the highly dimorphic reproductive nuclei. Sexual dimorphism in the reproductive tract is a product of Müllerian inhibiting substance (MIS), as well as the sex steroids. Males with a genetic deficiency in MIS signaling are sexually males, leading to the presumption ...[more]