Ontology highlight
ABSTRACT:
SUBMITTER: Liu Q
PROVIDER: S-EPMC2679021 | biostudies-literature | 2009 Mar
REPOSITORIES: biostudies-literature
BMC bioinformatics 20090317
<h4>Background</h4>Understanding the constituent domains of oncogenes, their origins and their fusions may shed new light about the initiation and the development of cancers.<h4>Results</h4>We have developed a computational pipeline for identification of functional domains of human genes, prediction of the origins of these domains and their major fusion events during evolution through integration of existing and new tools of our own. An application of the pipeline to 124 well-characterized human ...[more]