Ontology highlight
ABSTRACT:
SUBMITTER: Cha SW
PROVIDER: S-EPMC2679358 | biostudies-literature | 2008 Oct
REPOSITORIES: biostudies-literature
Cha Sang-wook SW Lee Jong-Woo JW Hwang Yoo-seok YS Chae Jeong-Pil JP Park Kwon Moo KM Cho Hee Jung HJ Kim Dong Sun DS Bae Yong Chul YC Park Mae Ja MJ
Experimental & molecular medicine 20081001 5
We have previously shown that the inhibition of fibroblast growth factor (FGF) signaling induced endodermal gene expression in the animal cap and caused the expansion of the endodermal mass in Xenopus embryos. However, we still do not know whether or not the alteration of FGF signaling controls embryonic cell fate, or when FGF signal blocking is required for endoderm formation in Xenopus. Here, we show that FGF signal blocking in embryonic cells causes their descendants to move into the endoderm ...[more]